Mitral transcatheter edge-to-edge repair (mTEER) is a catheter-based procedure that brings portions of the native mitral valve’s leaflet edges together to reduce regurgitation rather than replacing the valve. The STS/ACC Transcatheter Valve Therapy (TVT) Registry tracks the safety, procedural results, and follow-up outcomes of this treatment through its mitral leaflet clip data collection pathway. This information supports evaluation of repair effectiveness in everyday clinical practice.
For patients undergoing mTEER, the registry collects standardized information about clinical history, health status, treatment indications, procedural details, and outcomes. Repair-specific information includes the devices used, their locations, successful implantation, the amount of remaining mitral regurgitation, and the mean pressure gradient across the mitral valve. These measurements help assess the reduction in leakage and blood flow through the repaired valve.
Important complications monitored include bleeding, stroke, vascular injury, cardiac perforation, leaflet injury, device embolization, and the need for additional mitral valve treatment. The registry also records single-leaflet device attachment and complete clip detachment, allowing programs to evaluate complications directly related to the repair device and its attachment to the valve.
Follow-up data are collected at 30 days and one year to assess survival, functional status, valve function, and patient-reported health status. Echocardiographic findings document residual regurgitation and mitral valve gradients, while the Kansas City Cardiomyopathy Questionnaire (KCCQ-12) helps measure the patient’s experience of symptoms, activity limitations, and quality of life. Accurate documentation and complete follow-up are important to understanding outcomes beyond the procedure itself.
The TVT Registry is also approved to meet the national registry participation requirement within Medicare’s coverage policy for eligible mitral TEER procedures; other patient, provider, and hospital requirements must also be satisfied. Beyond coverage requirements, registry participation supports benchmarking, research, and continuous quality improvement, helping structural heart programs strengthen the safety and effectiveness of mitral valve repair care.